An enzyme-linked immunosorbent assay for detection of botulinum toxin-antibodies.
Identifieur interne : 000665 ( Main/Exploration ); précédent : 000664; suivant : 000666An enzyme-linked immunosorbent assay for detection of botulinum toxin-antibodies.
Auteurs : Dirk Dressler [Allemagne] ; Frank Gessler ; Pawel Tacik ; Hans BigalkeSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2014.
English descriptors
- KwdEn :
- MESH :
- chemical , blood : Antibodies.
- chemical , immunology : Botulinum Toxins.
- Animals, Computer Simulation, Enzyme-Linked Immunosorbent Assay, Mice, Models, Biological, ROC Curve, Transillumination.
Abstract
Antibodies against botulinum neurotoxin (BNT-AB) can be detected by the mouse protection assay (MPA), the hemidiaphragm assay (HDA), and by enzyme-linked immunosorbent assays (ELISA). Both MPA and HDA require sacrifice of experimental animals, and they are technically delicate and labor intensive. We introduce a specially developed ELISA for detection of BNT-A-AB and evaluate it against the HDA.
DOI: 10.1002/mds.25956
PubMed: 25073795
Affiliations:
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Le document en format XML
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Both MPA and HDA require sacrifice of experimental animals, and they are technically delicate and labor intensive. We introduce a specially developed ELISA for detection of BNT-A-AB and evaluate it against the HDA.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Basse-Saxe</li></region><settlement><li>Hanovre</li></settlement></list><tree><noCountry><name sortKey="Bigalke, Hans" sort="Bigalke, Hans" uniqKey="Bigalke H" first="Hans" last="Bigalke">Hans Bigalke</name><name sortKey="Gessler, Frank" sort="Gessler, Frank" uniqKey="Gessler F" first="Frank" last="Gessler">Frank Gessler</name><name sortKey="Tacik, Pawel" sort="Tacik, Pawel" uniqKey="Tacik P" first="Pawel" last="Tacik">Pawel Tacik</name></noCountry><country name="Allemagne"><region name="Basse-Saxe"><name sortKey="Dressler, Dirk" sort="Dressler, Dirk" uniqKey="Dressler D" first="Dirk" last="Dressler">Dirk Dressler</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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